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2009
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| Demestre, M., Messerli, S. M., Celli, N., Shahhossini, M., Kluwe, L., Mautner, V., & Maruta, H. 2009. CAPE (Caffeic Acid Phenethyl Ester)-based propolis extract (Bio-30) suppresses the growth of human neurofibromatosis (NF) tumor xenografts in mice. Phytotherapy Research, Feb; 23(2): 226-30. |
| Gleichmann, M., Collis, L., Smith, P.J.S. and Mattson, M. 2009. Simultaneous Single Neuron Recording of O2 Consumption, [Ca2+]i and Mitochondrial Membrane Potential in Glutamate Toxicity. J. of Neurochemistry. 109:644-655. |
| Heart, E., Cline, G.W., Collis, L.P., Pongratz, R.L. Gray J. and Smith, P.J. S. 2009. Role for malic enzyme, pyruvate carboxylation and mitochondrial malate import in the glucose-stimulated insulin secretion. Am J Physiol Endocrinol Metab. Jun;296(6):E1354-62. |
| Huang, L. Cormie, P., Messerli, M.A., and Robinson, K.R. 2009. The Involvement of Calcium and Integrins in Directional Responses of Zebrafish Keratocytes Exposed to Electric Fields. J. Cell. Physiol. Apr;219(1):162-72. |
| Kasinathan, R.S., Goronga, T., Messerli, S.M., Webb, T.R and Greenberg, R.M. 2009. Modulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel. The FASEB Journal. Vol. 24:1- 8. fj.09-137091. Sept. 2 [Epub ahead of print]. |
| Messerli MA, Collis LP & Smith PJS. 2009. Ion trapping with fast response, ion-selective microelectrodes enhances detection of extracellular ion channel gradients . Biophys. J. Feb 18;96(4):1597-605. |
| Messerli, S. M., Ahn, M-R., Kunimasa, K., Yanagihara, M., Tatefuji, T., Hashimoto, K., Mautner, V., Uto, Y., Hori, H., Kumazawa, S., Kaji, K., Ohta, T., & Maruta, H. 2009. Artepillin C (ARC) in Brazilian Green Propolis selectively blocks the oncogenic PAK1 signaling and suppresses the growth of NF tumors in mice. Phytotherapy Research, Mar; 23(3): 423-7. |
| Messerli, S. M., Demestre, M., Ahn, M. R. Yanagihara, M., Tatefuji, T., Uto, Y., Hori, H., Mautner, V., Hashimoto, K., Kumazawa, S., Ohta, T., & Maruta, H. (2009). Anti-PAK1 products Bio 30 and Brazillian Green Propolis Extract (GPE) suppress the growth of human NF and glioma xenografts in mice. American Association of Cancer Research (AACR) 100th Annual Meeting, April 18-22, Denver, Colorado. (abstract) |
| Messerli, S. M., Graham, D. M., Messerli, M. A., Menachery, A., Pethig, R., & Smith, P. J. 2009. Measurement of hydrogen ion activity in the intercellular space of schwannoma tumors. Biophysical Journal, 96 (3), 632a-633a. (abstract) |
| Messerli, S. M., Kasinathan, R. S., Morgan, W., Spranger, S., and Greenberg, R. M. 2009. Schistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibility. Mol Biochem Parasitol. 167: 54-59. |
| Peyot, M. Gray, J.P., Lamontagne, J., Smith, P.J.S., Holz, G.G., Madiraju, M., Prentki, M. & Heart, E. 2009. Glucagon Like Peptide-1 Induced Signaling and Insulin Secretion do not Drive Fuel and Energy Metabolism in Primary Rodent Pancreatic beta-Cells. PLoS. 4(7) (e6221): 1-10. |
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2008
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| Collis, L.P., Li, H., Gleichmann, M., Mattson, M.P. and Smith, P.J.S. 2008. Glutamate excitotoxicity and energy metabolism studied in the single neuron. Society for Neuroscience (abstract) |
| Collis, L.P., Li, H., Sanger, R.H., Cline, G., Mcnay, E.C. Smith, P.J.S., Hardwick, M. and Jonas, E.A. 2008. The metabolic basis of BCL-xL dependent neuroprotection and neuronal signaling. Society for Neuroscience (abstract) |
| Holz, G.G., Heart, E., Leech, C.A. 2008. Synchronizing Ca2+ and cAMP oscillations in pancreatic {beta}-cells: a role for glucose metabolism and GLP-1 receptors? Focus on "Regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic {beta}-cell: a computational approach. Am. J. Physiol. Cell Physiol. 294: C4-C6. |
| Li, H., Chen, Y., Jones, A.F., Sanger, R.H., Collis, L.P., Flannery, R., McNay, E.C., Schwartzenbacher, R., Bossy, B., Bossy-Wetzel, E., Bennett, M.V.L., Pypaert, M., Hickman, J.A., Smith, P.J.S., Hardwick, J.M. and Jonas, E.A. 2008. BCL-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons. PNAS. 105(6): 2169-2174. |
| Menachery, A., Messerli, S. M., Pethig, R., Smith, P. J. (2008), Dielectrophoresis as a method of isolating cells for the purpose of establishing a stably transfected cell line, Gordon Research Conference, Bioelectrochemistry, University of New England Biddeford, ME (abstract) |
| Messerli, M.A., Kurtz, I. and Smith, P.J.S. 2008. Characterization of Optimized Na+ and Cl- liquid membranes for use with extracellular, self-referencing microelectrodes. Anal. Bioanal. Chem. 390(5): 1355-9. |
| Messerli, S. M., Menachery, A., Collis, L., Pethig, R., Zhao, J., Basu, A., and Smith, P. J. (2008), Measuring extracellular ion gradients in pseudo-tissues assembled via dielectrophoretic techniques. Gordon Research Conference, Bioelectrochemistry, University of New England Biddeford, ME (abstract) |
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Monshausen GB, Messerli MA, Gilroy S. 2008. Imaging of the yellow cameleon 3.6 indicator reveals that elevations in cytosolic Ca2+ follow oscillating increases in growth in root hairs of arabidopsis. Plant Physiol. Aug;147(4):1690-8.
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| Nuccitelli, R. Nuccitelli, P. , Ramlatchan, S., Sanger, R. and Smith, P.J.S. 2008. Imaging the electric field associated with mouse and human skin wounds. Wound Repair and Regeneration. 16 (3): 432-441. |
| Oesterle, A. L. 2008. Ion Selective and Amperometric Microelectrodes. P-97 Pipette Cookbook (pdf). Sutter Instruments. Chapter 12: 57-58. |
| Pethig, R., Menachery, A., Heart, E., Sanger R.H and. Smith, P.J.S. 2008. Dielectrophoretic assembly of insulinoma cells and fluorescent nanosensors into three-dimensional 'pseudo-islet' constructs. IET Nanobiotechnology. 2(2): 31-38. |
| Salvador-Recatala V, Schneider T, Greenberg RM. 2008. Atypical properties of a conventional calcium channel beta subunit from the platyhelminth schistosoma mansoni. BMC Physiol. Mar 26;8:6. |
| Shum, W.W, Da Silva, N., McKee, M, Smith, P.J, Brown, D., Breton, S. 2008. Transepithelial projections from basal cells are luminal sensors in pseudostratified epithelia. Cell. Dec 12;135(6):1108-17. |
| Twig,G., Elorza, A., Molina, A.J.A., Mohamed, H., Wikstrom, J.D., Walzer., G., Stiles, L., Haigh, S.E., Katz, S., Las, G., Alroy, J., Wu, M., Py, B.F., Yuan, J., Deeney, J.T., Corkey, B.E. and Shirihai, O.S. 2008. Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. The EMBO Journal. 27:433–446 |
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2007
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| Adams, D.S., Masi, A., Levin, M. 2007. H+ pump-dependent changes in membrane voltage are an early mechanism necessary and sufficient to induce Xenopus tail regeneration. Development. 134(7):1323-35. |
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Bordenstein S.R., Werren J.H. 2007. Bidirectional incompatibility among divergent Wolbachia and incompatibility level differences among closely related Wolbachia in Nasonia. Heredity. 99: 278-87
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| Da Silva N., Shum W.W. C, El-Annan J., Paunescu T.G., McKee M., Smith P.J.S, Brown D., Breton S. 2007. Relocalization of the V-ATPase B2 subunit to the apical membrane of epididymal clear cells of mice deficient in the B1 subunit. Am. J. Physiol: Cell Physiology. 293(1):C199-210. |
| Gray, J.P., Heck, D.E., Mishin, V., Smith, P.J.S., Hong, J.Y., Thiruchelvam, M., Cory-Slechta, D.A., Laskin, D.L., and Laskin, J.D. 2007. Paraquat increases cyanide-insensitive respiration in murine lung epithelial cells by activating an NAD(P)H: Paraquat Oxidoreductase: Identification of the enzyme as thioredoxin reductase. J. Biol. Chem. 282(11):7939-49. |
| Greenberg, R.M. 2007. Molecular target of the antischistosomal drug praziquantel. Future Microbiol. 2:265-8. |
| Heart, E. Smith, P.J.S. 2007. Rhythm of the {beta}-cell oscillator is not governed by a single regulator: Multiple systems contribute to oscillatory behavior, Am J Physiol Endocrinol Metab. 292(5):E1295-300. |
| Heart, E., Yaney, G., Corkey, R.F., Schultz, V., Luc, E., Liu, L., Deeney, J.T., Shirihai, O., Tornheim, K., Smith, P.J.S, and Corkey, B.E. 2007. Ca 2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl-succinate: comparison with glucose. Biochem J. 403(1):197-205. |
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Ioannidis P., Hotopp J.C., Sapountzis P., Siozios S., Tsiamis G., Bordenstein S. R., Baldo L., Werren J. H., Bourtzis K. 2007. New criteria for selecting the origin of DNA replication in Wolbachia and closely related bacteria. BMC Genomics. 20(8):182.
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| Kreitzer, M.A., Collis, L.P., Molina, A.J.A., Smith, P.J.S., Malchow, R.P. 2007. Modulation of extracellular proton fluxes from retinal horizontal cells of the catfish by depolarization and glutamate. Journal of General Physiology. 130: 169-182. |
| Levin M. 2007. Gap junctional communication in morphogenesis. Prog Biophys Mol Biol. 200794(1-2):186-206. Review. |
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Levin M. and Palmer A.R. 2007. Left-right patterning from the inside out: widespread evidence for intracellular control. Bioessays. 29(3):271-87. Review.
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Lew R.R. 2007. Ionic currents and ion fluxes in Neurospora crassa hyphae. Journal of Experimental Botany. 58(12):3475-81.
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| Lew, R. Levina, N.N. 2007. Turgor regulation of the osmosensitive cut mutant of neurospora crassa. Microbiology. 153(5):1530-7. |
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Lo, N., Paraskevopoulos C., Bourtzis, K., O'Neill, S. L., Werren, J. H., Bordenstein, S. R., Bandi, C. 2007. Taxonomic status of the intracellular bacterium Wolbachia pipientis. Int J Syst Evol Microbiol 57(3): 654-7.
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| Messerli, M.A., Corson, E.D., and Smith, P.J.S. 2007. Measuring extracellular ion gradients from single channels with ion-selective microelectrodes. Biophysical Journal. 92(7):L52-4. |
| Messerli, M.A., Robinson, K.R. 2007. MS Channels in Tip Growing Systems. Current Topics in Membranes. Vol. 58. Elsevier, Amsterdam. pp. 391-412. |
| Monshausen, G.B., Bibikova, T.N., Messerli, M.A., Shi, C. and Gilroy, S. 2007. Oscillations in extracellular pH and reactive oxygen species modulate tip growth of Arabidopsis root hairs. PNAS. 104 (52): 20996-21001. |
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Prabhakar, S., Messerli, S. M., Stemmer-Rachmimov, A., Liu, T., Samuel Rabkin, S., Martuza, R., and Breakefield, X. O. 2007. Treatment of implantable NF2 schwannoma tumor models with oncolytic herpes simplex virus G47Delta. Cancer Gene Therapy. 14(5):460-7.
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| Reid, B., Nuccitelli, R., Zhao. 2007. Non-invasive measurement of biolectric currents with a vibrating probe. Nature Protocols, 2:3, 1-9. |
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Sanogo Y.O., Dobson S.L., Bordenstein S.R., Novak R.J. 2007. Disruption of the Wolbachia surface protein gene wspB by a transposable element in mosquitoes of the Culex pipiens complex (Diptera, Culicidae). Insect Mol Biol. 16(2):143-54.
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| Smith, P.J.S., Sanger, R.S. and Messerli, M.A. 2007. Principles, development and applications of self-referencing electrochemical microelectrodes to the determination of fluxes at cell membranes. In: Methods and New Frontiers in Neuroscience. Ed. Adrian C. Michael. CRC Press. Ch. 18: 373-405. |
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2006
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| Adams, D.S., Robinson, K.R, Fukumoto, T., Yuan, S., Albertson, C. R., Yelick, P., Kuo, L., McSweeney, M., Levin, M. 2006. Early, H+-V-ATPase-dependent proton flux is necessary for consistentleft-right patterning of non-mammalian vertebrates. Development, 133: 1657-71. |
| Collis, L., Molina, A., Malchow, R.P., Smith P.J.S. Oxygen consumption in single horizontal cells: the metabolic cost of signal processing. (#566.6/II20) (Abstract) |
| Dai Y., Wang L., Wang H., Liu Y., Li N., Lyu Q., Keefe D.L., Albertini D.F., Liu L. 2006. Fate of centrosomes following somatic cell nuclear transfer (SCNT) in bovine oocytes. Reproduction, 131(6):1051-61. |
| Gray, J. P., V. Mishin, P. J. Smith, D. E. Heck, and J. D. Laskin. Adriamycin increases cyanide-insensitive respiration in tumor cells via activation of NADPH oxidase. #A198. Molecular Targets and Cancer Therapeutics. AACR-NCI-EORTC. (Abstract) |
| Greenberg, R.M. 2006. Praziquantel: Mechanism of action. In: Parasitic Flatworms: Molecular Biology, Biochemistry, Immunology and Physiology. Ed. Maule, A., Marks, N.J.: 269-281, CABI, Oxfordshire, UK. |
| Heart, E., Corkey, R.F., Wikstrom, J.D., Shirihai, O.S., Corkey, B.E. 2006. Glucose-dependent increase in mitochondrial membrane potential, but not cytoplasmic calcium, correlates with insulin secretion in single islet cells. Am J Physiol Endocrinol Metab, 290(1): E143-E148. |
| Jeziorski M.C., Greenberg R.M. 2006. Voltage-gated calcium channel subunits from platyhelminths: potential role in praziquantel action Int J Parasitol, 36(6): 625-32 . |
| Keefe D.L., Marquard K., Liu L. 2006. The telomere theory of reproductive senescence in women. Curr Opin Obstet Gynecol, 18(3): 280-5 . |
| Kohn, A.B., Lea, J.M., Moroz, L., Greenberg, R.M. 2006. Schistosoma mansoni: use of a fluorescent indicator to detect nitric oxide and related species in living parasites. Experimental Parasitology, 113(2): 130-3. |
| Kuzirian, A.M., Epstein, H.T., Gagliardi, C.J., Nelson, T.J., Sakakibara M. M., Taylor, C.C., Scioletti, A.B., Alkon, D.L. 2006. Bryostatin enhancement of memory in Hermissenda. Biol Bull 210(3): 201-14. |
| Lew, R.R., Levina, N.N., Shabala L., Anderca, M.I., Shabala S.N. 2006. Role of a mitogen-activated protein kinase cascade in ion flux-mediated turgor regulation in fungi. Eukaryot Cell, 5(3): 480-7 . |
| Li H., Jones, A.F., Collis, L.P., Sanger, R.H., Smith, P.J.S., Hardwick, J.M., Jonas, E.A. BCL-xL increases presynaptic vesicle pool size in hippocampus and alters synaptic vesicle release dynamics. (388.2/H8) (Abstract) |
| Messerli, S.M., Morgan, W., Birkeland, S.R., Bernier, J., Cipriano, M.J., McArthur, A. G., Greenberg, R.M. 2006. Nitric oxide-dependent changes in Schistosoma mansoni gene expression. Mol Biochem Parasitol. 150(2): 367-70. |
| Messerli, M.A., Robinson, K.R. and Smith, P.J.S. 2006. Electrochemical sensor applications to the study of molecular physiology and analyte flux in plants. In: Plant electrophysiology - Theory and Methods. (PDF: 1,955 Kb) Ed. Alexander G. Volkov. Springer Sections 4.1–4.5. |
| Navarro P.A., Liu, L, Ferriani, R.A., Keefe, D.L. 2006. Arsenite induces aberrations in meiosis that can be prevented by coadministration of N-acetylcysteine in mice. Fertil Steril 85 Suppl 1:1187-94 |
| Sahoo, S., Nuccitelli, P., Nuccitelli, R. The Bioelectric Field Imager: A new medical device for the diagnosis of melanoma. (Abstract) |
| Smith, P.J.S. and Remsen, D. 2006. Using Pharmabase to Perform Pharmacological Analyses of Cell Function. In Current Protocols in Bioinformatics: Cheminformatics. Eds. Baxevanis, A., Davison,.D., Page, R., Petsko, G., Stormo, G. and Stein. L. John Wiley and Sons. Supplement 13, Section 14.2, 14.2.1 - 14.2.17. |
| Twig, G., Graf, S.A., Wikstrom, J.D., Mohamed H., Haigh, S.E., Elorza, A., Deutsch, M., Zurgil, N., Reynolds, N., Shirihai, O.S. 2006. Tagging and tracking individual networks within a complex mitochondrial web with photoactivatable GFP. Am J Physiol Cell Physiol 291(1): C176-84. |
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| Alkon, D.L., Epstein, H., Kuzirian A., Bennett, C.M., Nelson T.J. 2005. Protein synthesis required for long-term memory is induced by PKC activation on days before associative learning. Proceedings of the National Academy of Sciences USA, 102(45):16432-7. |
| Beaulieu, V., Da Silva, N., Pastor-Soler, N., Brown, C.R., Smith, P.J.S., Brown, D., Breton, S. 2005. Modulation of the actin cytoskeleton via gelsolin regulates vacuolar H+-ATPase recycling. Journal of Biological Chemistry, 280:8452-8463. |
| Brown, M.A., Begley, G.S., Czerwiec, E., Stenberg, L.M., Jacobs, M., Kalume, D.E., Roepstorff, P., Stenflo, J., Furie, B.C., Furie, B. 2005. Precursors of novel Gla-containing conotoxins contain a carboxy-terminal recognition site that directs gamma-carboxylation. Biochemistry 44:9150-9159. |
| Garber, S.S., Messerli, M.A., Hubert, M., Lewis, R., Hammar, K., Indyk, E. and Smith, P.J.S. 2005. Monitoring Cl- movement in single cells exposed to hypotonic solution. Journal of Membrane Biology, 203:101-110. |
| Greenberg R. M. 2005. Ca2+ signalling, voltage-gated 2+ channels and praziquantel in flatworm neuromusculature. Parasitology: 131 Suppl. S97-108. |
| Li R., Chase, M., Jung, S.K., Smith, P.J.S., and Loeken, M.R. 2005. Hypoxic stress in diabetic pregnancy contributes to defective embryo gene expression and defective development by inducing oxidative stress. American Journal of Physiology-Endocrinology and Metabolism, 289: E591-E599. |
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MacLellan, J. D., Gowing, A., Gerrits, M., Smith, P.J.S., Sivitz, W., Wheeler, M. B., and Harper, M. E. 2005. Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without unoupling muscle cells. Diabetes, 54:2343-2350.
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| Messerli, M.A., Amaral-Zettler, L.A., Zettler, E., Jung, S.K., Smith, P.J.S., Sogin, M.L. 2005. Life at acidic pH imposes an increased energetic cost for a eukaryotic acidophile. Journal of Experimental Biology, 208:2569-2579. |
| Osbourn, D.M., Sanger, R. H., and Smith, P.J.S. 2005. Determination of single cell oxygen consumption with impedance feedback for control of sample-probe separation. Analytical Chemistry, 77(21):6999-7004. |
| Osbourn, D.M., Sanger, R.H., Smith, P.J.S. 2005. Development of impedance feedback to measure sample-probe separation for single cell electrochemical measurements. Biophysical Journal, 88:347A. |
| Pethig, R., Jakubek, L.M., Sanger, R.H., Heart, E, Corson, E.D., Smith, P.J.S. 2005. Electrokinetic measurements of membrane capacitance and conductance for pancreatic beta-cells. IEE Proc Nanobiotechnol: 152(6): 189-93 . |
| Twig, G., Graf, S.A., Messerli, M.A., Smith, P.J.S., Yoo, S.H., Shirihai, O.S. 2005. Synergistic amplification of beta-amyloid- and interferon-gamma-induced microglial neurotoxic response by the senile plaque component chromogranin A. American Journal of Physiology-Cell Physiology, 288:C169-C175. |
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Equipment
